摘要
腹腔外科感染病人,抗生素疗法占有重要地位。252例腹腔脓液普通培养,24.2%无菌生长。培养出的菌丛中,绝大多数为革兰氏阴性细菌,大肠艾希氏菌占32.5%。选用抗生素应考虑:①菌丛及其联合存在的多样性;②药物进入胆汁的量与速度;③血与组织中的浓度;④药物的抗菌谱,毒性和价格。
For the majority of patients presenting withintra-adbominal surgical infection, antibiotic therapywill be the mainstary of treatment, The incidence ofnegative cultures on peritoneal suppurative fluid in 252patients with surgical infection is 24.2 per centGram-negative bacteria predominate in aerobes cul-tured on peritoneal pus. E, coli is 32.5 per cent in thesecases. In choosing an antibiotic or antibiotics for treat-ment of surgical infection of the abdomen. several fac-tors must be considered (1) the diversity of the organ-isms and their coexistence; (2) amount and velocit ofantibiotic excretion into bile and the effect of increasedbiliary pressures; (3) serum and tissue levels; (4)antibacterial spectrum, toxicity and cost.
出处
《西安医科大学学报》
CSCD
1991年第4期360-362,共3页
Journal of Xi'an Medical University(Chinese)
关键词
外科感染
细菌
抗生素
surgical infection bacteria
antibioties
