摘要
为了解甘肃省 1996～ 2 0 0 0年疫苗相关麻痹型脊髓灰质炎 (脊灰 )病例 (VAPP)的发生情况 ,利用急性弛缓性麻痹病例监测系统有关资料对VAPP进行分析。结果显示 :1996～ 2 0 0 0年全省共接种口服脊灰疫苗 2 6 2 9万人份 ,发生VAPP 7例 ,发生率为 0 2 7/ 10 0万 ,其中首次服苗者发生 4例 ,发生率为 1 6 2 / 10 0万 ,接触者发生 3例 ,发生率为 0 11/ 10 0万 ;病例呈高度散发 ,年龄均 <3岁 ,男女之比为 6∶1,临床表现典型 ,所有病例都残留麻痹 ;病毒分离以Ⅱ型疫苗相关株为多。实现无脊灰后VAPP的影响不容忽视。
This study was to make clear the occurrence of vaccine associated paralytic poliomyelitis(VAPP)in recent 5 years in Gansu Province.We analysised VAPP by adopting the data of AFP surveillance system.The results showed that in 1996～2000 oral polio vaccine doses for 26,290,000 persons were given,the incidence of VAPP was 0.27/1,000,000(7cases),among them 4 cases were first-dose vaccinated infants,3 cases were contacts,the incidence were 1.62/1,000,000 and 0.11/1,000,000 respectively.The cases showed highly sporadic and were under three years old,the ratio of male to female was 6∶1.The clinical symptoms were typical,all cases remained paralyzed.The viruses isolated were mostly polio vaccine associated type Ⅱ strains. For realizing a polio-free country, VAPP is not to be neglected.
出处
《中国计划免疫》
2002年第3期135-137,共3页
Chinese Journal of Vaccines and Immunization
