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青海省阻断输入性脊髓灰质炎野病毒传播免疫活动效果评价 被引量:4

Evaluation on the Effects of Immunization Activities for Blocking the Transmission of Imported Wild-Type Poliovirus in Qinghai Province
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摘要 青海省 1999年 10月发生了输入性脊髓灰质炎 (脊灰 )野病毒引起的病例后 ,为阻断脊灰野病毒传播 ,开展了10次应急免疫、“扫荡”式免疫和周边地区强化免疫活动。为了解其效果 ,采用对比分析方法进行评价。结果显示 :“扫荡”式免疫活动各年龄组服苗人数均高于统计局人数 ;与 1994/1995年强化免疫的同一出生队列相比 ,3个出生队列人数分别增加 2 7 91%、11 5 9%、6 94% ,1个队列人数减少 2 45 % ;“扫荡”式免疫与强化免疫发现“零”剂次免疫儿童数是历次免疫活动中最多的 ,两次“扫荡”式免疫“零”剂次儿童数相比下降 6 18% ,表明“扫荡”式免疫和强化免疫效果显著。经近两年急性弛缓性麻痹 (AFP)病例流行病学和病毒学监测未发现脊灰病例和野病毒 ,表明免疫活动达到了阻断脊灰野病毒传播的目的。 We used comparative analysis method to evaluate the effects of ten times of emergency,mopping-up and supplementary immunizations for blocking the transmission of imported wild-type poliovirus after the occurrence of imported wild-type poliovirus in Oct.1999 in Qinghai Province.The results showed that the numbers of children of different age groups involved in mopping-up immunization were all higher than that calculated by statistics agency.Compared with the same birth cohorts in 1994/1995, three birth cohort population in supplementary immunization went up 27.91%,11.95% and 6.94% respectively,one went down 2.45%.The numbers of zero-dose immunized children in mopping-up and supplementary immunizations were found to be the highest than before and these children decreased 6.18% in the second mopping-up immunization than that in the first.These data showed that the effects of mopping-up and supplementary immunizations were significant.Through two-year follow-up of AFP case surveillance and virology testing,poliomyelitis cases and wild-type poliovirus had not been found.It demonstrates that immunization activities has achieved the objective of blocking the transmission of wild-type poliovirus.
出处 《中国计划免疫》 2002年第3期129-131,共3页 Chinese Journal of Vaccines and Immunization
关键词 青海 脊髓灰质炎疫苗 免疫 脊髓灰质炎野病毒 Oral poliovirus vaccine Immunization effect Wild-type poliovirus
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