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^(13)N-NH_3PET显像诊断垂体微腺瘤的初步结果

The preliminary result in the diagnosis of pituitary microadenoma using dynamic ^(13)N-NH_3PET imaging
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摘要 目的 初步探讨^(13)N-氨(NH_3)PET动态显像诊断垂体微腺瘤的价值。方法 21例无垂体病史的住院病人行^(13)N-NH_3PET垂体显像,2例垂体微腺瘤患者,均经MRI、内分泌激素测定、临床表现等确诊,进行动态^(13)N-NH_3PET显像。结果 正常垂体^(13)N-NH_3PET显像垂体形态呈类圆形,垂体上缘平坦,垂体高度为1.06±0.12cm,垂体在颈内动脉显影后10s内显影。2例垂体微腺瘤患者垂体形态异常,垂体上缘膨隆,垂体高度分别为1.75cm和1.62cm,垂体显影时间延迟,分别在颈内动脉显影后20s和30s时显影。垂体SUV值分别为3.96和3.28,与丘脑放射性计数比值分别为1.58和1.27。结论 ^(13)N-NH_3PET显像可诊断垂体微腺瘤,其表现为垂体形态异常,垂体上缘膨隆,垂体高度增大,垂体显影时间延迟。^(13)N-NH_3PET显像诊断垂体微腺瘤的机制和价值需进一步研究。 To study the value of 13N - NH3PET imaging in diagnosing pituitary microadenoma.Methods 'N - NH.i pituitary PET imaging was performed in 21 normal subjects and 2 pituitary microadenomas whose diagnosis were confirmed by MRI, endocrine hormones and clinical presentations. Results In 'N - NH3PET images, normal pituitary gland showed a plane upper margin, and the average height were 1.06±0. 12cm in sagittal view. The pituitaries were seen in 10 seconds after the internal carotid. In the two cases of pituitary microadenomas, the upper margins of pituitary were convex, and the heights were 1. 75cm and 1. 62cm respectively. The pituitaries were seen in 20 and 30 seconds after the internal carotid. The standard uptake values(SUV) of pituitary were 3.96 and 3.28, and the ratios of pituitary to thalamus were 1.58 and 1.27. Conclusions 13N - NH3PET imaging can be used to diagnose the pituitary microadenoma, and its presentations in 13N - NR3PET images were convex upper margin, increasd pituitary height and delay of pituitary imaging.
出处 《影像诊断与介入放射学》 2001年第4期199-201,共3页 Diagnostic Imaging & Interventional Radiology
关键词 ^13N-NH3PET显像 诊断 垂体微腺瘤 放射性核素显像 Pituitary Tomography, Emission - computed I3N - ammonia Adenoma
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  • 1Shirasawa N,Yamanouchi H.Glucocorticoids induce glutamine synthetase in folliculostellate cells of rat pituitary glands in vivo and in vitro[].Journal of Anatomy.1999
  • 2Hutchins GD,Schwaiger M,Rosenspire KC,et al.Noninvasive quantification of regional blood flow in the human heart using 13 N-ammonia and dynamic positron emission tomographic imaging[].Journal of the American College of Cardiology.1990
  • 3Rosenspire KC,Schwaiger M,Mangner TJ,et al.Metabolic fate of 13 N-ammonia in human and canine blood[].The Journal of Nuclear Medicine.1990

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