摘要
目的 :观察冠状动脉成形术 (PTCA)对老年冠脉狭窄患者心肌复极的影响。方法 :连续测量了 6 8例冠状动脉狭窄老年患者 PTCA术前术后体表心电图的 QT间期与 QT离散度 (QTd) ,并与 5 3例无狭窄对照组比较。结果 :冠状动脉狭窄组较无狭窄组 QT间期显著延长 ,QTd明显增加 (QTm ax分别为 :45 3± 43m s和 392± 35 m s;QTc-max分别为 :482± 49m s和 439± 37ms;QTd为 74± 33m s和 2 9± 15 m s;QTcd为 78± 37ms和 32± 17m s,P<0 .0 1) ;PTCA使 QT间期缩短 ,QTd缩小 (QTcm ax:术前 482± 49ms,术后 1周为 45 2± 40 ms;QTcd在术前 78±37ms,术后 2 4h内 6 3± 2 6 m s,术后 1周为 6 0± 32 m s;QTd在术前 75± 34 m s,术后 2 4h内为 5 8± 2 5 ms及术后 1周 5 6± 31ms,P<0 .0 5 )。结论 :心肌灌注增加明显缩短 QTd离散度 ,表明心肌复极获得改善 ,这可能有利于减少心律失常的发生。
AIM:To evaluate the effects of percutaneous coronary angioplasty(PTCA) on the myocardial repolarization in elderly patients with coronary artery disease. METHODS:QT intervals and QT dispersions(QTd) measured from 12-lead standard surface ECG are consecutively assessed in the 68 patients with coronary stenosis intervened by PTCA,and compared with that in 53 ones without coronary stenosis.RESULTS:Compared with control group.QT internal and QTd both significantly increased in coronary stenosis group(QTmax:453±43 ms vs 392±35 ms;QTcmax:482±49 ms vs 439±37 ms;QTd:74±33 ms vs 29±15 ms;QTcd:78±37 ms vs 32±17 ms,P<0.01);While compared with pre-PTCA among the stenosis group,QT internal and QTd both decreased after PTCA(QTcmax:pre-PTCA 482±49 ms vs 1 week post-PTCA 452±40 ms;QTcd:pre-PTCA 78±37 ms vs 24 h post-PTCA 63±26 ms as well as week post-PTCA 60±32 ms;QTd:pre-PTCA 75±34 ms vs24 h post-PTCA 58±25 ms as wel as 1 week post-PTCA 56±31 ms,P<0.05). CONCLUSION:Myocardial perfusion enhancement by PTCA can effectively improve the myocardial repolarization in elderly patients with coronary stenosis.
出处
《心脏杂志》
CAS
2002年第2期149-151,共3页
Chinese Heart Journal
