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肿瘤抑制基因PTEN的研究进展 被引量:20

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摘要 PTEN/MMAC1/TEP1基因是 1997年克隆到的一个新的肿瘤抑制基因 ,具有酪氨酸磷酸酶的活性 ,有促进细胞凋亡 ,参与细胞周期的调控以及抑制细胞的粘附及肿瘤转移的作用。本文阐述了PTEN的结构功能 ,以及在肿瘤抑制中的作用机制。
作者 周隽 吴强
出处 《癌变·畸变·突变》 CAS CSCD 2002年第2期131-134,共4页 Carcinogenesis,Teratogenesis & Mutagenesis
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参考文献17

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