摘要
目的 了解南昌地区亚临床甲状腺功能减退症 (SCH)的患病率。方法 于 1997年 12月～ 1998年 6月 ,对南昌地区的四县五区 2 110人 ,其中成人 14 4 2人 ,年龄为 (18～ 70岁 ) ;儿童 6 6 8人 ,年龄为 (3岁～ 6岁 11个月 ) ,进行甲状腺激素筛查测定。结果 (1)南昌地区SCH总患病率 6 .1% ,其中成人患病率为 4 .6 % ,儿童患病率 9.1% ,儿童患病率高于成人 (P <0 .0 0 1) ;(2 )女性患病率为 7.4 % ;男性患病率为 4 .9% ,女性患病率高于男性 (P <0 .0 5 ) ;(3)SCH患病率与年龄结构比表明 :成人组 :6 0岁以上年龄组患病率最高 10 .4 % ,其次 5 0岁组 (5 .7% )和 18岁组 (5 .6 % ) ,但后两组比较差异无显著性 ,说明两个年龄段皆为患病高峰期。儿童组则以 3岁年龄组 ,患病率最高 (15 .9% ) ,其次是 6岁年龄组 (9.5 % ) ,两者自比或与成人组比较 ,差异皆有显著性 (P <0 .0 5 ) ;(4)SCH的患病率与甲状腺肿的发生无明显相关性。结论 南昌地区SCH的患病率较高 。
Objective To investigate the prevalence of subclinical hypothyroidism (SCH) in Nanchang area. Methods TSH, TT 3 and TT 4 levels in 2110 subjects were determined in Nanchang area including four counties and five districts. Results (1) The overall SCH prevalence in Nanchang area was 6.1%; being 9.1% in children, which was higher than that in adults (4.6%, P<0.001). (2) The SCH prevalence in women was 7.4%, higher than that in men (4.9%, P<0.05). (3) The relationship between the SCH prevalence and the age showed that the highest SCH prevalence in adults was in the 60 years old group (10.4%), followed by the 50 years old group (5.7%) and the 18 years old group (5.6%), but there was no difference between the latter two groups. In children, the highest SCH prevalence was 3 years old group (15.9%), followed by the 6 years old group (9.5%), and significant differences existed between the prevalences of these two groups and that of the adult group (P<0.05). (4) The SCH prevalence was not related with the occurrence of goiter. Conclusion The SCH prevalence is high in Nanchang area and is related to age and sex.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2002年第2期127-129,共3页
Chinese Journal of Endocrinology and Metabolism
