摘要
目的 :研究血清乙肝病毒 (HBV)的含量与HBV -DNA致病的关系及HBV -DNA含量与丙氨酸氨基转移酶(ALT)的相关性。方法 :以聚合酶链反应 (PCR)法对乙肝患者的血清进行HBV -DNA定量分析 ,同时检测ALT及乙肝两对半。结果 :大多数无症状携带者 (ASC)及HBeAg 阳性的乙肝患者的病毒血症水平较高 ,抗 -HBe阳性的慢性肝炎及肝硬化患者病毒水平依次减低 ,HBeAg 阳性及ALT的异常检出率随HBV -DNA滴度升高而增加。结论 :HBV
Objective:To study the relationship of content and pathogenesis of HBV_DNA and the correlation between HBV_DNA content and ALT.Methods:The serum HBV_DNA quantification in patients with hepatitis B was analysed with PCR,the ALT and HBV_DNA_markers were detected at the same time.Results:The Levels of virermia in most of asymptomatic carriers and hepatitis B patients with HBe-Antigen positive were fairly higher,which was successively decreasing in chronic hepatitis with Anti-HBe positive and cirrhosis patients.Rate of abnormality detection of HBe-antigen positive and ALT was increasing as the titer of HBV_DNA rose.Conclusion:The quantitative analysis of HBV_DNA is favourable for the clinical diagnosis and curative effect observation.
出处
《现代医药卫生》
2002年第2期86-87,共2页
Journal of Modern Medicine & Health
