摘要
研究了S 亚硝基谷胱甘肽 (GSNO)对偶氮二异丁腈 (AIBN)引发亚油酸过氧化和苯乙烯聚合的抑制作用 .GSNO的抑制作用可能归结为反应中生成的氮氧自由基的抑制活性 .EPR证据表明 ,含有AIBN和GSNO的DMSO溶液在无氧和 5 0℃下 ,生成了谷胱甘肽巯基 ,2 氰基 2 丙基氮氧自由基 .
S-Nitrosoglutathione (GSNO) exhibits inhibition effect on linoleic acid peroxidation and on styrene polymerization, using 2,2′-azobisisbutylnitrile (AIBN) as the initiator. Heating a solution of GSNO and AIBN in DMSO under argon produced an EPR signal, which was attributed to glutathiyl 2-cyano-2-propyl aminoxyl radical by comparison with the EPR spectrum obtained with a solution of NO and AIBN under the same experimental conditions. The results suggested that GSNO was converted to an aminoxyl radical and acted as such in the inhibition experiments.
出处
《化学学报》
SCIE
CAS
CSCD
北大核心
2002年第3期524-527,共4页
Acta Chimica Sinica
基金
国家自然科学基金 (No .2 0 0 72 013)资助项目
