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血浆内5—羟色胺含量与肺心病的关系

PLASMA 5-HYDROXYTRYPTAMINE(5-HT) AND COR PULMONALE
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摘要 用荧光法测定42例肺心病急性期血浆5-羟色胺(5-HT)、5-羟吲哚乙酸(5-HIAA)的含量变化,结果显示:5-HT、5-HIAA 值显著高于支气管炎发作期和对照组;肺心病缓解后,5-HT、5-HIAA 值显著下降.肺心病伴呼吸、心脏衰竭及肾功能不全者5-HT 值高于无并发症患者,5-HT Plasma 5-hydroxytryptamine(5-HT) and 5-hydroxyindolcacetic acid(5-HIAA) were determined by fluorometry in 42 patients with cor pulmonale.It was found that their plasma 5-HT and 5-HIAA concentrations were much higher than those in patients with bronchitis(P<0.01),and those in the control group(P<0.01).With the subsidenc of acute at- tack of pulmonale,the concentrations were reduced significantly.In patients with cor pulmonale complicated by respiratory failure,heart failure,or renal insufficiency the 5-HT value was high- er than that in ptients with no complications(P<0.05).It was also found that the prognosis of cor pulmnale patients with a higher plasma 5-HT concentration was relatively poor.
出处 《皖南医学院学报》 CAS 1991年第4期243-245,共3页 Journal of Wannan Medical College
关键词 肺心病 血清学 血浆 5-hydroxytryptamine cor pulmonale
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