摘要
目的 :探讨血清 CA12 5在肺癌诊断和疗效观察中的价值。方法 :检测 87例肺癌治疗前后血清 CA12 5水平。结果 :以 CA12 5 >35 U/m L 为阳性界值 ,CA12 5对肺癌的诊断率为 4 7.1% ,其阳性检出率分别是 :鳞癌 4 1.7% ,腺癌 4 3.3% ,未分化癌 6 1.9% ,未分化癌与鳞癌 CA12 5水平比较 ,有显著差异 (P<0 .0 5 )。CA12 5水平还与临床分期有关 , b、 期明显高于 b、 a、 b、 a 期 (P<0 .0 5 )。结论 :血清 CA12 5水平对肺癌诊断具有一定的价值 ,是临床分期、疗效观察及预后判断的重要参考指标。
Objective: To probe into the clinical diagnosis and effective values in serum carbohydrate antigen 125(CA125) in patients with lung cancer. Methods: Serum CA125 was tested by enzyme linked immunnosorbent assay(ELISA) in 87 patients with lung cancer before and after treatment. Results: The cut off value of serum CA125 level was 35 U/mL. The diagnostic ratio of serum CA125 in lung cancer was 47.1 %. The positive ratio of serum CA125 in the cases of squamous cell carcinoma,adenocarcinoma and undifferentiated carcinoma respectively were 41.7 %, 43.3 % and 61.9 %.The level of serum CA125 in adenocarcinoma and undifferentiated carcinoma compared with squamous cell carcinoma was significantly higher( P <0.05),and the level also was significantly higher in stage Ⅲ b and Ⅳ compared with Ⅰ b,Ⅱ a,Ⅱ b and Ⅲ a ( P <0.05).Conclusion:The determination of serum CA125 for lung cancer is a useful diagnosis method.It can be used as an adjunctive test in clinical stages,observation of effect and judgement of prognosis.
出处
《肿瘤研究与临床》
CAS
2002年第2期99-100,共2页
Cancer Research and Clinic
