摘要
目的 :探讨尿螨病的临床症状 ,为诊治提供依据。方法 :对经流行病学确诊的 6 9例尿螨病患者进行尿常规检查、血常规检查、血清总IgE、螨特异性IgE检测、皮肤挑刺试验 ;对 11例尿螨病患者进行膀胱镜检查。 结果 :尿螨病患者的主要临床症状为夜间遗尿和尿频、尿急、尿痛等尿路刺激症状 ,其次为颜面和 /或下肢水肿、尿量异常、蛋白尿、大量上皮细胞尿等。白细胞计数在 ( 5 .3～ 11.4)× 10 9/L之间 ,多数患者白细胞分类中的嗜酸性粒细胞有不同程度的增高 ,一般在 0 .0 5～ 0 .0 9之间 ,最高达 0 .48;嗜酸性粒细胞计数多在 0 .5× 10 9/L～ 0 .14× 10 9/L之间。尿螨阳性患者血清总IgE、螨特异性IgE水平明显高于尿螨阴性者 ,差异有显著性 (P <0 .0 1,P <0 .0 5 )。皮肤挑刺试验结果显示 :“ ”者 39例 ,“ ”者 41例 ,“ +”者 36例 ,“±”者 2 5例 ,“ -”者 185 3例 ,阳性率分别为 1.96 %、2 .0 6 %、1.81% ,可疑者为 1.2 5 % ,阴性率为 92 .92 %。 11例患者膀胱镜检查发现 ,膀胱三角区粘膜上皮增生、肥厚 ,固有膜内有浆细胞、淋巴细胞浸润 ,有聚集的粉红色脓肿 ,膀胱内壁轻度小梁性改变 ,侧壁局部呈充血样改变 ,毛细血管充血扩张。结论 :尿螨病的临床症状虽与泌尿系统其他疾病有雷同之处 ,但仍有诊断?
Objective: The clinical symptom of urinary acariasis was under analysis in order to provide the evidence to early diagnosis of urinary acariasis. Methods: The routine urine examination,routine blood examination, total IgE, specific IgE of mites in serum, dermal sensitivity test were detected for the 69 patients with urinary acariasis that had been identified with the investigation of epidemiology respectively. The test of cystoscopy was taken for the 11 patients with urinary acariasis respectively. Results: The main clinical manifestations were irritation sign of bladder,such as enuresis in the night, frequency of micturition, urgency of urination, urodynia, hydrops of face and lower limb, abnormality of urine volume, proteinuria, large epithelial cells in urine and so on. The leukocyte count was in the range from 5.3 ×10 9/L to 11.4 ×10 9/L. The eosinophilic granulogyte count was high in the classification of leukocytes and was in the range from 0.5 ×10 9/L to 0.14 ×10 9/L (normal 0.05 - 0.09 , the highest 0.48 ). The levels of total IgE and specific IgE of acarida mites were higher in the positive patients than those in negative patients ( P < 0.01 , P < 0.05 ). The results of dermal sensitivity test showed that the positive number of '', '', '+','±', '-' were 39,41,36,25, 1 835 respectively, the positive rates of '', '', '+','±','-' were 1.96 %, 2.06 %, 1.81 %, 1.25 %, 92.92 % respectively.The tests of cystoscopy for 11 patients showed that the epithelium mucosae cells were active proliferation, pachynsis in trigone of urinary bladder, plasmocyte and lymphocytic infiltration and pink abscess in membrane propria, the change of trabecularism and congestion and telangiectasis in inter wall of bladder.Conclusions: Urinary acariasis was deficient in specific clinical symptom. The characteristic clinical manifestations of urinary acariasis were positive of mites in urine, high level of total of IgE, specific IgE of acarida mites in serum, positive of dermal sensitivity test.
出处
《中国媒介生物学及控制杂志》
CAS
CSCD
2002年第2期116-118,共3页
Chinese Journal of Vector Biology and Control
