摘要
目的研究与探讨不同理化方法处理后的异种肌腱移植对受体血清免疫的影响及其作用机理。方法用山羊脾细胞刺激BALB/C品系小鼠获取血清抗体,将新鲜的山羊肌腱和经不同理化方法处理后的肌腱组织在体外分别与鼠血清抗体结合反应,进行酶联免疫吸附测定。结果经过理化方法处理后的肌腱组织对血清抗体的吸附能力明显减弱(P<0.05)。结论适当的理化处理方法能够降低异种肌腱刺激受体的血清免疫反应。
Objective To study and probe into the influence of heterogeneous tendon s grafting on re-ceiver's serum immunoreactions as well as the working mechanism of the tendons after they had been treated with different physical or chemical means.Methods Serum antibody through stimulating mouse of BALB/C breed with goat spleen cells was collected,and then connected it with the antigen of fresh goat tendons or the tendons having been treated with different physical or chemical means.Finally,ELISA tests were made to determine the strength of the tendons' antigenicity.Results Having been treated with such physical or chemical means,the capacity of the tendon tissue's absorbing serum anti-body weakens notably.Conclusion Appropriate physical or chemical means can weaken the receiver's serum immunity reaction towards heterogeneous tendons.
出处
《实用医药杂志》
2002年第5期363-365,共3页
Practical Journal of Medicine & Pharmacy
关键词
肌腱移植
异种移植
血清免疫
Tendon Heterogeneous grafting Serum immunity
