摘要
目的 :探讨噻氯匹啶对Ⅱ型糖尿病患者血糖、血脂、血液流变学的影响。方法 :治疗组 40例 ,同时口服格列齐特 80mg ,bid和噻氯匹啶 2 5 0mg ,qd。对照组 2 0例 ,口服格列齐特 80mg ,bid。疗程均为 2周。结果 :治疗组有效率87.5 % ,对照组有效率 6 5 .0 % (P <0 .0 5 ) ;治疗组血脂、血液流变学指标均有改善 ,与对照组比较 ,差异有极显著性 (P <0 .0 1)。结论 :噻氯匹啶可作为Ⅱ型糖尿病患者的辅助治疗药物。
Objective:To study the effect of ticlopidine on blood glucose, lipid and blood rheology in patients with type Ⅱdiabetes mellitus. Methods:40 patients in the treatment group were given each 80 mg of gliclazide b.i.d. and 250 mg of ticlopidine q.d., while only 80 mg of gliclazide b.i.d were administerd to each of 20 cases in the control group. The course lasted 2 weeks in both groups. Results:The clinical cure rate were 87.5% and 65.0% in the treatment group and control group respectively. The situation of blood lipid profiles and blood rheology was much better improved in the treatment group than in the control group. The differences between these parameters of the two groups are highly significant (P<0.01). Conclusion:Ticlopidine can be used as an auxiliary medicine in the treatment of patients with type Ⅱ diabetes mellitus.
出处
《医药导报》
CAS
2002年第5期282-283,共2页
Herald of Medicine
关键词
噻氯匹啶
格列齐特
糖尿病
Ⅱ型
Ticlopidine
Gliclazide
Type Ⅱdiabetes mellitus
