摘要
目的 评价心肌肌钙蛋白Ⅰ (cardiactroponinⅠ ,cTnI)对危重新生儿心肌损伤的诊断价值。方法 用化学发光免疫法及免疫抑制法分别测定 30例健康儿 (足月儿 1 4例 ,早产儿 1 6例 )及 66例危重儿血清中cTnI与CK -MB水平。并作心电图与超声心动图检查。结果 cTnI正常值范围为 0～ 1 93ng/mL。无心肌损伤危重儿均 <2ng/mL ,而 >2ng/mL心肌损伤率 1 0 0 % ,明显高于CK -MB升高者 46 1 5 % ,P <0 0 5。结论 cTnI对危重新生儿心肌损伤有高度特异性 ,明显增高者示预后不良。
Objective To evaluate the diagnostic value of cardiac troponinⅠin myocardial injury in neonate with severely ill.Methods The serum level of cardiac troponinⅠ(cTnI)and creatine phosphate kinase MB(CK-MB)were determinated by chemiluminescence enzyme immunoassay and immunoinhibit assay respectively in 30 health neonates and 66 new borns with severely ill; and all neonate were examined with electrocardiograms and ultrasonic cardiogram.Results The level of cardiac troponin Ⅰ in the health children ,s serum was from 0 to 1.93 ng/mL,and it ,s level of the severe neonate with no myocardial injury was less than 2 ng/mL ,while ones which cardiac troponin level is more than 2 ng/mL were all myocardial injury(100%),it was higher than the change of CK-MB(46.5%)significantly, P <0.05.Conclusion cTnIwas high specificity for diagnosis in myocardial injury of the severe neonate,and which cTnI increase significantly show prognosis is bad.
出处
《中国急救医学》
CAS
CSCD
北大核心
2002年第5期270-271,共2页
Chinese Journal of Critical Care Medicine
