摘要
对24例确诊的重症药疹住院病例的性别、年龄、原发病、可疑致敏药物、临床表现及实验室检查结果进行了统计分析,并以168例同期住院的非重症药疹患者为对照。发现两组在年龄、性别、既往药物过敏史及服用可疑致敏药物的数量方面无显著性差异,而与所用药物种类及原有基础疾病有显著相关性。服用卡马西平的患者及原发病为神经系统疾病的患者更易发生重症药疹。重症药疹患者更易合并发热、肝肾功能损害及外周血象改变。
Twenty four cases of severe type of drug eruption inpatients from the Third Hospital of Peking University between 1994 to 2000 were analyzed and 168 inpatients with non severe type of drug eruption from the same hospital at same period served as control. The results indicated that age ,sex, previous history of drug allergy, and dose of medication used are not predisposing factors of svere type of drug eruption;while the type of medication used and previous diseases played an important role in inducing severe type drug eruption. The patients with neurological disease were more likely to develop severe type of drug eruptions and carbamazepine was more likely to induce severe type of drug eruption.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2002年第5期290-291,共2页
Journal of Clinical Dermatology
