摘要
目的 探讨辣椒辣素溶液膀胱灌注治疗顽固性女性尿道综合征的可能性。 方法 对32例诊断为慢性尿道综合征且久治不愈的女性患者行辣椒辣素溶液 (10 0 μmol/L ,10 0ml)膀胱灌注治疗 ,随访其症状改善程度。 结果 15例得到长期随访 ,其中 14例 (94 % )有效 ,5例 (33% )症状完全消失。疗效维持时间最长者已超过 12个月 ,有 8例在 3～ 6个月内复发 ,占 5 3%。对复发病例再次灌注治疗。灌注后膀胱容量增加 ,有局部烧灼痛 ,无其他副作用。 结论 辣椒辣素膀胱灌注疗效好 ,维持时间长 ,可作为顽固性尿道综合征的一种有效治疗手段。
Objective To evaluate intravesical capsaicin for the treatment of obstinate urethral syndrome in female. Methods Thirty two female patients suffering from urethral syndrome not relieved on various therapeutic methods for a long time were treated by bladder instillation of 100 ml of 100 μmol/L capsaicin. Results 15 cases were followed up for more than 12 months with improvement in 94%.The symptoms were totally disappeared in 33% of the patients.The syndrome recurred in 53% between 3～6 months. 1 case did no response to the treatment. Bladder instillation of capsaicin induced an increase of the bladder volume.Some burning sensation was the only side effect. Conclusions Intravesical capsaicin could be a long lasting effective therapeutic method for patients with obstinate urethral syndrome.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2002年第5期282-284,共3页
Chinese Journal of Urology
