摘要
目的 :了解长春地区下呼吸道感染者细菌分布及耐药情况。方法 :采用普通痰细菌培养法及药敏法测定细菌分布及细菌耐药性。结果 :细菌阳性分离率 2 6.5 % ;革兰阴性 ( G-)杆菌占首位( 72 .5 % ) ,其中克雷伯杆菌、铜绿假单胞菌、大肠埃希菌、不动杆菌、肠杆菌为优势菌 ;革兰阳性( G+ )球菌占第 2位 ( 2 2 .9% ) ,其中链球菌、表皮葡萄球菌、金黄色葡萄球菌为优势菌。大部分 G-杆菌对亚胺培南、氟喹诺酮类、头孢霉素三代及丁胺卡那霉素有较好的敏感性 ;G+球菌对头孢霉素二代、头孢霉素三代、万古霉素及亚胺培南较敏感。结论 :长春地区下呼吸道感染患者感染细菌以 G-杆菌占首位。亚胺培南、丁胺卡那霉素、头孢他啶及头孢哌酮在 G-杆菌中抗菌活性最强。万古霉素、亚胺培南对 G+
Objective: To investigate the distribution and resistance of pathogens causing lower respiratory tract infection (LRTI) in Changchun area. Methods: Sputum culture was followed by drug susceptibility test. Results: The postive isolation rate of bacteria was 26.5% (503/1 869) in which G - bacilli was major, took up 72.5% (365/503). According positive rate of them K. lebsiella , P. aeruginosa E. coli , A. cinetobacterl and Enterobacter in order were predominant, respectively; G + cocci was second (22.9%, 115/503) . Among them, Streptococcus , S. epidermidis S. aureus are predominant, respectively. The majority of G - bacilli showed lower resistant rate in comparison with imipenem, quinolones,the third generation of cephalosporins and tobramycin. G + cocci had lower resistant rate in comparison with the second and third generation of cephalosporins, vacomycin and imipenem. Conclusion: G - bacilli is the predominant in LRTI . Imipenem, tobramycin, ceftazidime and cefoperazone are the most effective to G - bacter, while the vacomycin and imipenem are the most effective to G + bacteria.
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2002年第2期182-184,共3页
Journal of Jilin University：Medicine Edition
