摘要
本文用单株单克隆体、HBc 抗体及 HBs 抗体以 ABC 法检测病毒性乙型肝炎、肝硬化、肝癌组织中的 HBsAg 及 HBcAg 的分布。结果提示病毒性乙型肝炎、肝硬化、肝癌近半数以上病例有完整的乙型肝炎病毒(HBV)复制,使人认识到 HBV 持续长期存在,可能直接引起肝癌的危险性。HBsAg 及 HBcAg 在上述三者组织中细胞内的分布及形态观察均以胞浆弥漫型占优势,局灶型及胞膜型少见,是否暗示胞浆弥漫型肝炎易向肝硬化乃至肝癌发展的倾向,这有待动态研究予以证明。
HBsAg and HBcAg were detected by their monoclonal antibodies and ABCmethod in liver tissue with hepatitis B,cirrhosis and hepatocarcinoma.The resultsshowed that the positive detective rates of HBV markers were gradually raised inhepatitis B,cirrhosis and hepatocarcinoma,suggesting that HBV being persistent asa high risk factor for developing hepatocarcinoma,and that the positivity of one orboth of HBsAg and HBcAg in the plasma of liver cell indicated the tendency ofdevelopment of hepatic carcinoma.
出处
《天津医药》
CAS
1991年第11期664-666,共3页
Tianjin Medical Journal
关键词
肝硬变
乙型肝炎
肝肿瘤
癌
抗原
bepatitts B cirrhosis
hepatocarcinoma
HBsAg
HBcAg
