摘要
对53例经手术切除的肺神经内分泌癌进行了病理形态学及临床生物学特性的研究,根据分化程度,神经内分泌癌可以分为三型:高分化型(类癌)、中分化型(不典型类癌)、低分化型(小细胞肺癌)。在临床生物学方面,手术时肿瘤体积,高分化型为6.91cm^3,中分化型为23.82cm^3,低分化型为31.32cm^3,差别显著(P<0.05);中位生存时间,高分化型为78^+个月,中分化型为30个月,低分化型为14个月,差异极其显著(P<0.001)。在病理形态学和超微结构上三型间亦明显不同,有加以区分的实际意义。
The histological morphology, biological behavior and prognosis of 53 cases of neuroe-ndocrine carcinoma (NEC) of lung were evaluated. Bases on histological manifestations NEC was divided into 3 types: the well differentiated type (WDT, ie. typical carcinoid), the intermediate differentiated type (IDT ie.atypical carcinoid) and the poor differentiated type (PDT, ie.small cell lung carcinoma). The average size of the tumor at operation was 6.91cm in WDT, 23.82cm in IDT and 31.32cm in PDT and the median survival time was 78, 30 and 14 months respectively(p<0.001). The biological behavior and prognosis were obviously different with the 3 types of neuroendocrine carcinoma and therefore the morphological type of the tumor should be well ascertained.
出处
《空军总医院学报》
1992年第1期8-11,F003,共5页
Journal of General Hospital of Air Force,PLA
