摘要
本文用 APAAP 免疫组化方法对20例急性白血病进行免疫分型初步研究,结果表明17例(85%)急性白血病有特征性或相关性标志,其中非 T-ALL10例(Ⅰ、Ⅱ、Ⅲ型为3、2和5例),T-ALL 2、AML 1、AMMoL 及双表型各2例。不能确定表型1例(5%)及无标志者2例(10%),认为免疫组化有利于鉴别形态特殊的白血病。临床(瑞氏染色)诊断、细胞化学及免疫组化检测三项结果一致者9/16(56.25%),临床诊断与免疫组化两项一致者3例,临床诊断与细胞化学结果一致,而免疫表型不能确定及无标志者2例,三项结果均不一致者2例。10例住院患者的临床表现及预后与免疫表型无相关性。
Preliminary immunological classification of 20 cases with acute leukemia wascarried out by APAAP immunohistochemical method.The results showed that therewere characteristic or interrelated markers in 17/20(85%) cases.Out of the 17 cases,10 were non-TALL(type I.II and III being 3,2,and 5,respectively);TALL,AML,AMMoL and double phenotypic leukemia were 2,1,2 and 2,respectivly;Undeterminedand leukemia without marker were 1(5%)and 2(10%),respectively.Immunohistoche-mical method are thought favourably to identify the subtype of special leukemia.Clinical diagnosis,cytochemistry and immunohistochemistry were consistent in 9 cases(56.25%).The results of clinical diagnosis were in accord with immunohistochemicalanalysis in 3 cases.2 cases(12.5%) in whom phenotype were undelined or withoutmarker in immunohlstochemistry appeared to be consistent in results of clinicaldiagnosis and cytochemistry.2 cases(12.5%) had no association in the 3 analyticindexes.Clinical features and prognosis of 10 hospitalized patients were not signifi-cantly related to immunophenotype.
出处
《天津医药》
CAS
1991年第1期31-35,共5页
Tianjin Medical Journal
关键词
白血病
免疫组化
免疫分型
Immunological clssificatlon of leukemia
Immunohistochemistry
Double phenotypic leukemia
