摘要
目的 探讨急性下呼吸道感染儿童的肺炎衣原体感染情况及其检测方法。方法 对 74例急性下呼吸道感染患儿进行咽拭子肺炎衣原体PCR检测以及血清ELISA检测肺炎衣原体IgM、IgG抗体 ,对于仅IgG阳性者 ,再留取恢复期血清检测IgG抗体。结果 74例患儿咽拭子PCR标本中测得 11例阳性。血清ELISA肺炎衣原体IgM阳性 7例 ,肺炎衣原体IgG阳性 2 1例 ,其中有 2例IgM、IgG均阳性。仅IgG阳性者中恢复期血清IgG 4倍增高者 5例。诊断为肺炎衣原体患者 ,咳嗽发生率 10 0 % ,发热发生率为 6 6 .7% ,喘息发生率为 2 5 .0 % ,并主要见于幼儿 ,胸片片状阴影发生率 10 0 %。结论 咽拭子肺炎衣原体PCR阳性检出率与血清抗体检出率无明显差异 。
Objective To explore the invasive chlamydia pneumoniae infection in children with acute lower respiratory tract infection.Methods PCR method was used to detect chlamydia pneumoniae DNA and ELISA to detect serum IgM and IgG antibodies respectively.For those with positive IgG, serum IgG antibody was detected again.Results Among the 74 cases, 11 were positive for chlamydia pneumoniae DNA.ELISA revealed that 7 cases were positive for chlamydia pneumoniae IgM, 21 for IgG and 2 for both IgM and IgG.For 5 cases of positive IgG, the serum IgG antibody at the restoration stage was increased by 4 fold.In the children diagnosed as having chlamydia pneumoniae infection, the incidence of cough, fever and gasp was 100%, 66.7% and 25.0% respectively.Conclusion There was no significant difference in the positive rate between PCR and the serum IgM and IgG antibodies.Both of them could be used to detect the chlamydia pneumoniae infection.
出处
《华中医学杂志》
CAS
2002年第2期67-68,共2页
Central China Medical Journal
关键词
儿童
下呼吸道感染
肺炎衣原体
诊断
Child Lower respiratory tract infection Chlamydia pneumoniae
