摘要
吸烟是目前唯一公认的危险因素。近来研究认为生育史与胰腺癌相关 ,但也有互相矛盾的结论。为了评价首胎年龄和生育数与胰腺癌的发生可能存在的关系 ,作者做了以医院为基础的病例对照研究。结果发现 ,首胎年龄与生育数均与胰腺癌相关 ,经吸烟、饮酒、体重指数、胆石症、胆囊切除术、糖尿病、慢性胰腺炎和胃部分切除术调整后相关性仍存在。低龄、高龄生育及生育 3胎 (OR =3 10 ,95 %CI=1 6 5～5 82 )
Smoking is presently the only generally accepted risk factor for pancreatic cancer. In recent studies, reproductive history has been associated with pancreatic cancer, but with contradictory results. In order to evaluate a possible association between age of first parturition and the number of births and pancreatic cancer, we conducted a case control study with a hospital background. Association between age of first parturition and the number of births and pancreatic cancer was found, and it remained after adjustment for cigarettes smoking, alcohol consumption, body mass index, cholelithiasis, cholecystectomy, diabetes mellitus, chronic pancreatitis and partial gastrectomy. Young age of first parturition and high reproductive history, such as 3 or more births were risk factors for pancreatic cancer.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2002年第4期294-295,共2页
Medical Journal of Chinese People's Liberation Army
基金
全军首批临床重大技术资助项目
关键词
胰腺肿瘤
生育史
病因学
病例对照研究
危险因素
pancreatic neoplasms
reproductive history
etiology
case control studies
