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沈阳地区幽门螺杆菌耐药情况的研究 被引量:11

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摘要 目的:观察研究H.pylori对克拉霉素、甲硝唑、阿莫西林及四环素的耐药情况,指导临床治疗。 方法:从消化性溃疡、肿瘤或慢性胃炎患者的胃黏膜中分离培养出H.pylori共30株,利用E-test方法进行药物的MIC测定,观察耐药情况。 结果:30株H.pylori中有7株对克拉霉素耐药,12株对甲硝唑耐药,2株对四环素耐药,未发现对阿莫西林耐药的H.pylori菌株。耐药率分别为23.3%,40%,6.7%及0%。 结论:在辽宁省沈阳市H.pylori对克拉霉素及甲硝唑的耐药率比较高,而对阿莫西林高度敏感,临床选择H.pylori根除方案时要考虑这一点。
出处 《世界华人消化杂志》 CAS 2002年第4期480-481,共2页 World Chinese Journal of Digestology
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  • 1[1]Walsh JH,Peterson WL. The treatment of Helicobacter pylori infection in the managementof peptic ulcer disease. N Engl J Med 1995;333:984-991
  • 2[2]Franzin L, Pennazio M, Cabodi D, Paolo Rossini F, Gioannini P. Clarithromycin and amoxicillin susceptibility of Helicobacter pylori strains isolated from adult patients with gastric or duodenal ulcer in Italy. Curr Microbiol 2000;40:96-100
  • 3[3]Kihira K, Satoh K, Saifuku K, Kawakami K, Ishino Y, Kimura K, SuK. Rabeprazole, amoxycillin and low- or high- dose clarithromycin for cure of Helicobacter pylori infection. Aliment Pharmacol Ther 2000; 14:1083-1087
  • 4[4]Houben MH, Hensen EF, Rauws EA, Hulst RW, Hoff BW, Ende AV, Kate FJ, Tytgat GN. Randomized trial of omeprazole and clarithromycin combined with either metronidazole or amoxycillin in patients with metronidazole-resistant or -susceptible Helicobacter pylori strains. Aliment Pharmacol Ther 1999;13:883-889
  • 5[5]Sakurai K, Takahashi, Yamaguchi Y, Yamada M, Kirihara K, KojimaT, Fujita R.Importance of drug selection and the use of sensitivity tests for the eradication therapy for Helicobacter pylori. Nippon Riinsho 1999;57:72-75
  • 6[6]Sharaara AI, Chedid M, Arai GF, Barada KA, Mourad FH. Prevalence of Helicobacter pylori resistance to metronidazole, elarithromycin, amoxycillin and tetracycline in Lelanon. Int J Antimierob Agents 2002;19:155-158
  • 7[7]Dunn BE,Cohen H, Blast MB Helicobacter pylori. Lin Microbiol Rev 1997;40:720-741
  • 8刘之武,李平,谢蓓,杨萍.天津地区部分人群幽门螺杆菌感染现状[J].新消化病学杂志,1996,4(12):718-718. 被引量:2
  • 9[9]Lahenz J, Borsch G. Highly significant change of the clinical course of relapsing and complicated peptic ulcer disease after cure of Helicobacter ylori infection. Am J Gastro enterol 1994;89:1785-1788
  • 10[10]Sung JJ, Chung SC, Ling TK, Yung MY, Leung VK, NgEK, LiMK, Cheng AF, Li AK. Antibacterial trentment of gastric ulcers associated with Helicbacter pylori. N Engl J Med 1995; 332 :139-142

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