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细胞外基质与肝脏肿瘤 被引量:7

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摘要 0 引言 近年来,随着对细胞外基质(extracelular matrix,ECM)研究的不断深入,对其功能也有了进一步的了解.目前认为细胞外基质不只是对细胞和组织起支架或骨架作用,而且对生理或病理状态下细胞的分化、增殖及基因表达均有非常重要的作用.在肝脏发生肿瘤时,细胞外基质及其降解酶基质金属蛋白酶(mamx metalloprotemases,MMPs)对肿瘤的发展、转移等有非常重要的影响.
作者 金博
出处 《世界华人消化杂志》 CAS 2002年第1期63-64,共2页 World Chinese Journal of Digestology
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  • 1Ooi LL. 3rd Yahya Cohen Lecture: the role of the myofibroblast like cell in hepatocellular carcinoma-host defence? Ann Acad Med Singapore 1999;28:342-346.
  • 2唐有为,姚希贤.肝癌细胞对星状细胞活化的调控作用[J].世界华人消化杂志,2001,9(2):202-204. 被引量:5
  • 3Faouzi S, Le Bail B, Neaud V, Boussarie L, Saric J, Bioulac Sage P, Balabaud C, Rosenbaun J. Myofibroblasts are responsible for collagen synthesis in the stroma of buman hepatocellular carcinoma: an in vivo and in vitro study. J Hepatol 1999;30:275-284.
  • 4Ito H, Miyazaki M, Nishimura F, Nakajima N. Secretion of extracellular matrix (fibronectin), growth factor ( transforming growth factor beta) and protease (cathepsin D)by hepatoma cells. Oncology 2000;58:261-270.
  • 5Le Bail B, Faouzi S, Bousssarie L, Guirouilh J, Blanc JF, Carles J、 Bioulac Sage P, Balabaud C, Rosenbaum J. Osteonectin /SPARC is overexpressed in human hepatocellular carcinoma. J Pathol 1999; 189:46-52.
  • 6周信达.肝癌复发转移防治的研究进展[J].世界华人消化杂志,1999,7(3):260-261. 被引量:22
  • 7Friedl P, Brocker EB. The biology of cell locomotion within three-dimensional extracellular matrix. Cell Mol Life Sci 2000;57:41-64.
  • 8Stefani AL, Basso D, Panozzo MP, Greco E, Mazza S, Zancanaro F, De Franchis G, Plebani M. Cytokines modulate MIA PaCa 2 and CAPAN-1 adhesion to extracellular matrix proteins. Pancreas 1999; 19:362-369.
  • 9Zvibel I, Halpern Z, Papa M. Extracellular matrix modulates expression of growth factors and growth-factor receptors in liver-colonizing colon-cancer cell lines. lnt J Cancer 1998;77:295-301.
  • 10Gulubova MV. Ito cell morphology, alpha-smooth musele actin and collagen type IV expression in the liver of patients with gastric and colorectal tumors.Histochem J 2000;32:151-164.

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  • 1DU Wei-Dong,ZHANG Yue-E,ZHAl Wei-Rong and ZHOU Xiao-Mei(Department of Pathology, Shanghai Medical University, Shanghai200032, China)(National Laboratory for Oncogenes and Related Genes, ShanghaiCencer Institute)See invited commentary on page 388.Dynamic changes of typeⅠ,Ⅲand N collagen synthesis and distribution of collagen-producing cells in carbon tetrachloride-induced rat liver fibrosis[J].World Journal of Gastroenterology,1999,5(5):397-403. 被引量:47
  • 2曾维政,蒋明德,褚桂珍,张建华,陈泰庆,楚人俊,邓桂英,张家碧.原位聚合酶链技术检测肝细胞癌组织内丙型肝炎病毒核酸及其意义[J].中华内科杂志,1994,33(11):747-750. 被引量:10
  • 3李季,田素礼,李巍,李福蕴.结直肠癌中PTEN的缺失表达及临床意义[J].世界华人消化杂志,2006,14(28):2771-2775. 被引量:7
  • 4李文.中草药抑制HBV—DNA的实验研究[J].中医杂志,1997,38(1):46-47. 被引量:34
  • 5袁桂清.全国乙肝防治研讨会[J].中华医学信息导报,1991,5:5-5.
  • 6罗远超 韦富祥.血清“两对半”出现模式[J].寻医问药,1997,:917-917.
  • 7MATHIEU E, MEHEUS L, RAYMACKERS J, et al. Characterization of the osteogenic stromal cell line MN7 : identification of secreted MN7 proteins using two - dimensional polyacrylamide gel electrophoresis, western blotting, and microsequencing[ J]. J Bone Miner Res, 1994, 9:903-913.
  • 8HAN Z, NI J, SMITS P, et al. Extracellular matrix protein 1 (ECM 1 ) has angiogenic properties and is expressed by breast tumor cells[J]. FASEB J, 2001, 15:988-994.
  • 9SERCU S, ZHANG M, OYAMA N, et al. Interaction of extracellular matrix protein 1 with extracellular matrix components: ECM 1 is a basement membrane protein of the skin [ J ]. J Invest Dermatol, 2008,128(6): 1 397-1 408.
  • 10DECKERS M M, SMITS P, KARPERIEN M, et al. Recombinant human extracellular matrix protein 1 inhibits alkaline phosphatase activity and mineralization of mouse embryonic metatarsals in vitro [J]. Bone, 2001, 28:14-20.

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