摘要
以 NBT/VB2 /蛋氨酸为 O· - 2 产生、检测体系 ,对自制低聚壳聚糖及其金属配合物进行了抗 O· - 2 活性研究 ,结果显示低聚壳聚糖及其金属配合物对 O· - 2 均具有明显的清除活性 .质量浓度为 0 .5× 1 0 - 2 g/m L时 ,壳聚糖对 O· - 2 的清除率达 80 .3 % ,其与氯化镧、醋酸铜、醋酸钴的配合物对 O· - 2 的清除率分别为98.9%、84.1 %、78.4% ;相同条件下 ,高分子壳聚糖和单糖对 O· - 2 没有明显的清除作用 ,清除率仅为 1 3 %、9.5 % .随着样品质量浓度降低 。
The O ·- 2 scavenging activity of low molecular weight chitosan(LMC) and its complexes with Cu(Ⅱ), Co(Ⅱ), La(Ⅲ) was investigated. Colorimetric method was used, where V B2 and Met were used as producing reagent and NBT as detecting reagent for O ·- 2. The results showed that when mass concentration of samples was 0 5×10 -2 g/mL, the O ·- 2 scavenging activity of LMC and LMC Cu(Ⅱ), LMC Co(Ⅱ), LMC La(Ⅲ) were 80 3%, 98 9%, 84 1% and 78 4% respectively, but those of high molecular weight chitosan(820 kD) and D Glucosamine were only about 13% and 9 5%. The scavenging activity of LMC and its complexes decreased with decrease in their mass concentration .
出处
《应用化学》
CAS
CSCD
北大核心
2002年第4期325-328,共4页
Chinese Journal of Applied Chemistry
基金
国家自然科学基金 (2 0 0 610 0 1)
海南省首届高校优秀中青年教师教学与科研奖励基金资助项目
