摘要
目的 加深对粘膜相关淋巴组织 (MALT)型淋巴瘤的认识。方法 复阅胃肠道MALT型淋巴瘤 30例 ,在HE诊断基础上做HP染色和免疫组化LCA、CD2 0、κ、λ、CK标记。结果 胃 16例 ,肠 14例。临床主要表现为腹胀腹痛 ,黑便或血便 ,腹部包块。病理改变以边缘区B细胞 (中心细胞样细胞 )为主 ,13例出现变异大细胞 ,3例以变异大细胞为主。 2 5例有淋巴上皮 (LEL)病变 ,18例有淋巴滤泡结构 ,2 1例见浆细胞浸润。17例HP阳性 ,30例CD2 0阳性。结论 胃肠道MALT型淋巴瘤与HP感染关系密切。
Objective To recognize further gastrointestinal extranodal marginal zone B-cell lymphoma(mucosa-associated lymphoid tissue lymphoma).Methods 30cases with MALT lymphoma were reviewed,HP stain and immunize organization chemical LCA.CD20.k.λ.CK markings were done under the basis of HE diagnosis.Results The major clinical symptoms were abdominal distention ,stomach-ache,blood stool and abdominal masses?The major pathological change was extranodal marginal zone B-cell.The mutant large cells were seen in 13 cases.3 cases were consisted of mainly mutant large cells,25 cases had lymph epithelium processes,18 cases had lymph follicle structures,21 cases had plasmacyte infiltration.HP positive in 17cases,and CD20 positive in 30 case.Conclusion There is a close relationship between MALT lymphoma and HP infection.According to the portion of the mutant large cells ,the low-grade MALT lymphoma may change into mid-grade or high-grade.
出处
《云南医药》
CAS
2002年第2期81-82,共2页
Medicine and Pharmacy of Yunnan
