摘要
本文介绍氟噻草胺合成工艺,以水合肼、三氟乙酸为原料合成2-甲砜基-5-三氟甲基-1,3,4-噻二唑;以对氟硝基苯、丙酮经过催化加氢、酰化、醇解合成N-(4-氟苯基[(\))0(-)]N-异丙基-2-羟甲基乙酰胺;及氟噻草胺的制备。
The article described the synthesis of flufenact,a herbicide. It抯 achieved via condensation of interediates, 2-methylsulfonyl-5-trifluoromethyl-1,3,4thiadiazol and N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl)acetamide. The former intermediate is prepared starting from hydrazine hydrate and trifluroracetic acid. The latter is obtained by using 4-nitro-fluorobenzene and acetone as starting materials through a series of reaction, such as catalytic hydrogenation, alcoholysis and amidation.
出处
《现代农药》
CAS
2002年第2期8-10,共3页
MODERN AGROCHEMICALS
