摘要
目的 :探讨孕前体重指数与妊娠期糖尿病 (GDM)发病率的关系 ,为预防GDM的发生提供科学依据。方法 :通过问卷获得研究对象的孕前体重 ;通过测量获得研究对象的身高、体重、腰围、髋围、股围、50g-GCT1h血糖、75g-OGTT空腹血糖、2h血糖等。统计方法采用非条件Logistic回归分析。结果 :单因素回归分析显示孕前体重高(RR=10.0227,95 %CI3.5860～28.0127)、孕前体重指数大(BMI)(RR=18.0482,95 %CI6.2437～52.1704)、孕前腰围大 (RR=3.3869,95 %CI1.6110～7.1205)增加孕妇发生GDM的危险 ,未发现孕前身高与GDM有关联 ;首诊腰围 (RR=4.2336,95%CI1.5095～11.8732)、首诊髋围 (RR=2.7634,95%CI1.0105～7.5575)、首诊股围 (RR=6.8422,95 %CI2.3299～20.0931)与GDM有关联 ,未发现首诊腰髋比与GDM有关联。非条件Lo gistic回归多因素分析表明:只有孕前BMI与GDM有关联。结论 :孕前BMI是GDM的独立危险因素。
Objective:To explore a relationship between pre-pregnancy BMI and the prevalence rate of GDM and to provide scientific informations of GDM for prevention.Methods: Pre-pregnancy was obtained by using questionnaire, some variables were measured including height,weight,waist circumference,hip circumference,thigh circumference, 50 g 1 hour blood glucose, 75 g GTT FBS and 2 hour blood glucose.Statistical Analysis :Relative risks and 95% confidence intervals were calculated by means of non-conditional logistic regression.Results: The risk for developing GDM was increasing with pre-pregnancy weight(RR=10.0227,95%CI 3.5860～28.0127)?pre-pregnancy BMI(RR=18.0482,95%CI 6.2437～52.1704)?pre-pregnancy waist circumference(RR=3.3869,95%CI 1.6110～7.1205),but no statistical difference was observed in pre-pregnancy height.The occurrence of GDM would increase in those women who had a big waist?hip and thigh circumference at the first examination. A non-conditional logistic regression covariate analysis showed that only pre-pregnancy BMI was independent risk factors for GDM.Conclusion: The incedence of GDM was related to pre-pregnancy BMI.
出处
《天津医科大学学报》
2002年第1期4-6,共3页
Journal of Tianjin Medical University
基金
国家自然科学基金资助
(编号39970661)
