摘要
以HAP/DOM(Ⅰ组)及HAP/DAP(Ⅱ组)方案治疗急性非淋巴细胞白血病30例(Ⅰ组12例,Ⅱ组18例)。其完全缓解率各为75%及72.2%。缓解需2.5及3.2疗程。1/2～2疗程时出现骨髓抑制,继而白细胞下降。骨髓抑制者缓解率高。
In order to test the efficacy of HAP/DOM and HAP/DAP chemotherapy regimen on indu-cing remission of acute nonlymphocytic leukemia(ANLL),we randomly assigned 30 children withANLL to recive either HAP/DOM regimen(group I,12 cases)or HAP/DAP regimen(groupⅡ,18 cases).We found that the complete remission(CR) rate was 75% in group Ⅰ and 72.2%in group Ⅱ.CR was achieved by about 2.5 and 3.2 regimen myelosuppression was observed ei-ther in the later half stage of the first regimen or in the second.The white blood cell count de-creased later on.Patients with bone marrow depression seemed to have a higher CR rate.BY ourclinical experience,relipse remains to be a challenge.The problems concerning with optimaltherapeutic regimen,intensive chemotherapy after remission and the continual therapy to achieveprolonged remission duration still remain controversial.
出处
《苏州医学院学报》
1991年第3期188-190,256,共3页
Acta Academiae Medicinae Suzhou
关键词
非淋巴细胞
白血病
完全缓解率
acute nonlymphocytic leukemia
complete remission rate
