摘要
目的 探讨无水酒精局部注射 (PEI)术治疗复发性肝癌对癌细胞血行播散的影响。方法 应用巢式RT PCR检测复发性肝癌患者PEI术前后周围静脉血液中肝癌细胞的变化。结果 2 9例复发性肝癌患者PEI术前有 14例 (4 8% )周围血液中肝癌细胞阳性者 ;PEI治疗 4次 (1个疗程 )后阳性者减至 2例 (7% )。
Objective To study the effect of PEI on disseminating HCC cells in the peripheral blood in patients with recurrent HCC. MethodsWe examined blood samples from 29 recurrent HCC patients by nested RT-PCR for the determination of AFP?mRNA before and 1, 2, 3 and 4 weeks after PEI.ResultsBefore PEI 14 (48%) patients out of the 29 cases with recurrent HCC were positive with AFP?mRNA. Four weeks after a course of PEI only 2 cases (7%) remained AFP?mRNA positive.ConclutionsPEI effectively eradicating disseminating HCC cells in the peripheral blood shows a favourable potential for the treatment of recurrent HCC.
出处
《中华普通外科杂志》
CSCD
北大核心
2002年第4期207-208,共2页
Chinese Journal of General Surgery
