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“消乳块胶囊”预防乳腺肿瘤的实验研究 被引量:4

Study on preventing the breast neoplasm with Xiao Ru Kuai capsule
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摘要 目的 采用消乳块胶囊对小鼠性腺与肝脏重量及血清内分泌激素水平的研究以了解其对乳腺肿瘤的预防作用。方法 以 8周龄雌性 NIH小鼠 15只 ,分为对照、低剂量 0 .4 8g/( kg· d)和高剂量 12 g/( kg· d)三组 ,每天灌胃 1次 ,连续 14天后处死 ;作血清 L H、FSH、PRL、TSH、E2 及 P测定和称取肝脏、子宫和卵巢重量。结果  ( 1)治疗组 E2 下降与 P升高 ,但无统计学意义 ;FSH下降则有统计学意义 ,P<0 .0 5 ,而 L H下降则没有统计学意义 ;此外 ,TSH下降不明显 ,PRL水平各组无差异。 ( 2 )治疗组除肝脏称重较对照组明显增加 ( P<0 .0 5 )外 ,子宫和卵巢等性腺重量无改变。结论 消乳块胶囊对小鼠体内内分泌激素水平有一定的调节作用 。
作者 王晓稼 郑树
出处 《实用肿瘤杂志》 CAS 北大核心 2002年第2期114-116,共3页 Journal of Practical Oncology
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