摘要
目的 观察特发性股骨头缺血坏死 (ANFH)的病理变化 ,探讨脂肪栓子及微血栓 ,分析坏死原因。方法 34个特发性ANFH的股骨头 ,采用苏木素 伊红、脂肪、微血栓和弹力纤维染色方法 ,光镜下观察股骨头内各部位的坏死和修复情况 ,确定脂肪栓子和微血栓的形态和分布状态。结果 坏死股骨头内骨髓细胞减少 ,脂肪组织增多 ,脂肪细胞肥大。血管中有大量脂肪栓子和微血栓 ,1 9个股骨头内发现脂肪栓子 ,2 1个发现微血栓 ,在 1例中显示骨髓内脂肪滴正从静脉破裂口进入静脉内。结论 脂肪栓塞是ANFH的重要原因 ,骨髓脂肪滴进入血管可能起动了ANFH并维持其发展。
Objectives To observe the pathological changes in avascular necrosis of the femeral head (ANFH),to find fat emboli and microthrombosis,and to analyze the necrotic causes. Methods The necrosis and repairment in the femoral head of patients with ANFH were observed by means of HE,fat,microthrombus and elastic fiber staining under ligh microscopy and the morphology and distribution of fat emboli and microthrombusi was determined in the same way.Results Hypertrophic fat cells,a decreased number of bone marrow cells and an increased number of fat cells in the necrotic fermoral head were found.There were a large number of fat emboli and microthrombusi in the vessels.Fat emboli was found in 19 fermoral heads and microthrombusi in 21 ones.Among all the sections,one showed a fat embolus entering the vein from the outside through a broken part of the vein.Conclusion Fat embolism is an important cause of the necrosis of the femoral head,and the fat drops of marrow in the vein may trigger and promote ANFH.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2002年第2期132-133,T003,共3页
Chinese Journal of Experimental Surgery
