摘要
目的探讨腭扁桃体摘除术联合雷公藤多甙与强的松治疗IgA肾病的远期疗效。方法将90例IgA肾病患者按腭扁桃体表型和个人意愿分为糖皮质激素药物治疗组(A组)31例和糖皮质激素联合扁桃体切除组(B组)59例。比较两组患者治疗与随访期间蛋白尿和血尿初次缓解时间、持续缓解时间及临床疗效。结果随访期间B组蛋白尿、血尿治疗总有效率显著高于A组(P<0.05或0.01)。B组蛋白尿、血尿初次缓解时间显著短于A组(P<0.01),且缓解持续时间长于A组(P<0.01)。结论腭扁桃体摘除术联合雷公藤多甙与强的松治疗IgA肾病,能够快速有效改善患者的蛋白尿、血尿症状,延长缓解时间,有助于取得良好的远期疗效。
Objective To investigate the long-term efficacy of tonsillectomy combined with GTW and prednisone in the treatment of IgA nephropathy.Methods 90 patients with IgA nephropathy were selected as the research objects and divided into group A (.receiving glucocorticoid drug therapy,31 cases)and group B (receiving glucocorticoid combined with tonsillectomy, 59 cases).The proteinuria and hematuria primary remission time,duration of remission and clinical efficacy between the two groups during treatment and follow-up were compared.Results The total effective rate of proteinuria and hematuria in group B was significantly higher than that in group A at different follow-up time (P<0.05 or 0.01).The initial remission time of proteinuria and hematuria in group B was significantly shorter than that in group A (P<0.01),and the duration of remission was longer than that in group A (P<0.01).Conclusion Tonsillectomy combined with GTW and prednisone in the treatment of IgA nephropathy can quickly and effectively improve the patient's proteinuria,hematuria symptoms, prolong the remission time,and help to achieve good long-term results.
作者
于二峰
高明
杨亚茹
杨全德
Yu Erfeng;Gao Ming;Yang Yaru;Yang Quande(Zhumadian City First People's Hospital,Zhumadian 463000,Henan,China)
出处
《临床心身疾病杂志》
CAS
2019年第1期94-96,121,共4页
Journal of Clinical Psychosomatic Diseases
基金
河南省医学科技攻关计划项目(编号201502019).
