摘要
目的:在口服柳氮磺吡啶肠溶片的基础上,对比隔药大艾灸与普通大艾灸治疗强直性脊柱炎的临床疗效。方法:将64例寒湿痹阻型强直性脊柱炎患者随机分为隔药大艾灸组和大艾灸组,各32例。在口服柳氮磺吡啶肠溶片的基础上,大艾灸组以背部大椎至长强穴为中心,左右宽约10 cm为施灸部位,进行1 h艾灸;隔药大艾灸组在施灸前,将纱布在混匀的药酒与生姜汁中浸湿,贴敷于大艾灸组相同的施灸部位,进行1h艾灸。两组治疗均每周1次,3次为一疗程,共治疗3个疗程。观察两组患者治疗前后症状量化评分、枕墙距、Schober试验及全血C反应蛋白(CRP)、红细胞沉降率(ESR)水平的变化,并评定临床疗效。结果:两组患者治疗后症状量化评分、枕墙距及全血CRP、ESR水平均低于治疗前(均P<0.05),Schober试验指标高于治疗前(均P<0.05),治疗后隔药大艾灸组症状量化评分、Schober试验及全血CRP、ESR水平均优于大艾灸组(均P<0.05),枕墙距两组间比较差异无统计学意义(P >0.05)。隔药大艾灸组总有效率为90.0%(27/30),高于大艾灸组的73.3%(22/30,P<0.05)。结论:隔药大艾灸联合柳氮磺吡啶肠溶片治疗寒湿痹阻型强直性脊柱炎疗效显著,可明显减轻患者疼痛症状,改善枕墙距、Schober试验等体征,提高其生活质量。
Objective To compare the clinical efficacy between herb-separated moxibustion and conventional moxibustion on ankylosing spondylitis(AS) based on oral administration of sulfasalazine enteric-coated tablets. Methods A total of 64 patients with AS of cold-dampness obstruction type were randomly divided into an herb-separated moxibustion group and a conventional moxibustion group, 32 cases in each one. Based on oral administration of sulfasalazine enteric-coated tablets, the patients in the conventional moxibustion group were treated with moxibustion at the area with Dazhui(GV 14) to Changqiang(GV 1) as center and about 10 cm in width;the moxibustion was given for 1 hour. In the herb-separated moxibustion group, the gauze was soaked in the medicinal liquor and ginger juice, and placed on the same moxibustion area as the conventional moxibustion group, followed by moxibustion for 1 hour. The treatment in the two groups was given once a week, three treatments constituted a course and totally three courses were given. The symptom quantification score, occipital-wall distance, Schober test, C-reactive protein(CRP) and erythrocyte sedimentation rate(ESR) levels were observed before and after treatment in the two groups, and the clinical efficacy was evaluated. Results Compared before treatment, the symptom quantification score, occipital-wall distance, CRP and ESR levels were lower but the Schober test was higher after treatment in the two groups(all P<0.05). The symptom quantification score, Schober test, CRP and ESR levels in the herb-separated moxibustion group were superior to those in the conventional moxibustion group(all P<0.05), but no significant difference was observed on occipital-wall distance(P >0.05). The total effective rate was 90.0%(27/30) in the herb-separated moxibustion group, which was higher than 73.3%(22/30) in the conventional moxibustion group(P<0.05).Conclusion The herb-separated moxibustion combined with sulfasalazine enteric-coated tablets has significant efficacyfor AS with cold-dampness obstruction type, which could obviously relieve pain symptoms, improve occipital-wall distance, Schober test and other physical signs, and improve the quality of life.
作者
田中华
王新义
张玉飞
田元生
TIAN Zhong-hua;WANG Xin-yi;ZHANG Yu-fei;TIAN Yuan-sheng(Department of Encephalopathy,Affiliated Hospital of Henan Academy of Traditional Chinese Medicine,Zhengzhou 450000,China;Henan Academy of Traditional Chinese Medicine,Zhengzhou 450000;Henan University of TCM)
出处
《中国针灸》
CAS
CSCD
北大核心
2019年第1期44-48,共5页
Chinese Acupuncture & Moxibustion
基金
2016年河南省第二批科技攻关项目:162102310371
关键词
强直性脊柱炎
寒湿痹阻型
隔药灸
艾灸疗法
柳氮磺吡啶肠溶片
药酒
ankylosing spondylitis (AS),cold-dampness obstruction type
herb-separated moxibustion
moxibustion therapy
sulfasalazine enteric-coated tablets
medicinal liquor
