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急性髓系白血病靶向治疗新进展 被引量:4

New advances on targeted therapy for acute myeloid leukemia
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摘要 急性髓系白血病(acute myeloid leukemia,AML)是成人最常见的急性白血病。针对AML,虽然近年来在完全缓解(complete remission,CR)率与无病生存(disease free survival,DFS)率上都有明显提高,但还有将近一半患者不能获得长期生存,复发和难治仍然是影响AML疗效的瓶颈。过去的十几年来,AML的靶向药物不断推陈出新,但真正被证实能改善患者预后的药物非常有限。
作者 蒋灵旭 罗颖婉 佟红艳 JIANG Ling-xu;LUO Ying-wan;TONG Hong-yan(MDS Center, Department of Hematology,the First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310003,China)
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2018年第12期1198-1202,共5页 Chinese Journal of Practical Internal Medicine
基金 国家自然科学基金面上项目(81470290).
关键词 急性髓系白血病 靶向治疗 靶向免疫治疗 acute myeloid leukemia targeted therapy targeted immunotherapy
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