摘要
目的:探讨吸入用布地奈德混悬液和硫酸特布他林雾化液雾化吸入治疗慢性阻塞性肺疾病急性加重期(AECOPD)效果及安全性。方法:选取2016年10月～2017年9月我院收治的AECOPD患者116例随机分为干预组(吸入用布地奈德混悬液+硫酸特布他林雾化液雾化治疗,58例)和对照组(硫酸特布他林雾化液雾化治疗,58例),比较两组治疗效果及药物不良反应发生情况。结果:干预组疗效显著优于对照组[96.55%vs 82.76%,(P<0.05)]。两组治疗期间心悸、头晕、尿潴留、震颤、口干、胃肠不适发生率比较差异无统计学意义(P>0.05)。结论:吸入用布地奈德混悬液联合硫酸特布他林雾化液雾化吸入治疗AECOPD具有显著疗效和较高用药安全性。
Objective To explore the effect and safety of inhalation of budesonide suspension and terbutaline sulfate aerosol inhalation in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Method Select 116 case of AECOPD patients in our hospital during Oct.,2016~ Sept.,2017 as studying object,randomly divided into intervention group(inhalation with cloth to Ned mixed suspension + terbutaline sulfate atomized liquid atomization treatment,58 cases)and control group(terbutaline sulfate atomized liquid atomization treatment,58 cases),compared two groups of patients with therapeutic effect and adverse drug reactions occurred.Result The efficacy of the intervention group was significantly higher in the control group [96.55% vs.82.76%,P<0.05]. The incidence of palpitations,dizziness,urine retention,tremor,dry mouth and gastrointestinal discomfort were not statistically significant(P <0.05).Conclusion AECOPD was treated by inhalation of budesonide suspension combined with terbutamine sulfate in the treatment of AECOPD with significant efficacy and high safety.
作者
林桂鹏
许楚湖
苏春燕
Lin Guipeng;Xu Chuhu;Su Chunyan(Chaozhou chaoan people's hospital,Pharmacy,515636)
出处
《北方药学》
2019年第1期13-14,共2页
Journal of North Pharmacy
关键词
布地奈德混悬液
硫酸特布他林雾化液
雾化
慢性阻塞性肺疾病
Budesonide suspension
Terbutaline sulfate spray
Atomization
Chronic obstructive pulmonary disease
