摘要
目的 前瞻性对照观察内镜下套扎 (EVL)与硬化 (EVS)治疗肝硬化食管静脉曲张破裂出血的疗效。方法 将 10 7例慢性乙型肝炎后肝硬化并发食管静脉曲张活动出血患者 ,随机分成套扎组 (EVL组 )及硬化剂组 (EVS组 ) ,于入院 2 4h内分别行镜下EVL及EVS治疗 ,10～ 14d重复治疗。结果 两组急诊止血率分别为EVL组 91% (5 1/5 6) ,EVS组 90 % (4 6/5 1) ,再出血率EVL组为 5 % (3 /5 6) ,EVS组为 6% (3 /5 1) ,两者治疗效果相仿 (P >0 .0 5 )。EVL组副作用发生率明显高于EVS组 (P <0 .0 5 ) ,但均能自行消失 ,无须特殊处理。结论 内镜下套扎和硬化术治疗食管静脉曲张出血均安全有效 。
Objective To assess the efficacy and safety of band ligation versus sclerotherapy in controling acute esophageal variceal bleeding. Methods 107 liver cirrhosis patients with esophageal varices bleeding were randomly assigned into two groups:band ligation group(Ⅰ) with 56 patients or to sclerotherapy guoup (Ⅱ) with 51 patients. Both endoscopic therapies were performed within 24 hours of addmision. Repeated produres were performed in the following 10～14 days. Results No statistical differences were observed between two groups in term of control of active bleeding (91 vs 90) and recurrence of bleeding(5% vs 6%). GroupⅠ had significantly more side effects than groupⅡ(29% vs 12%, P <0.05). However, there were no serious complications in either groups. Conclusion Both endoscopic variceal band ligation and sclerotherapy are safe and effective in controling active bleeding and rebleeding from esophageal varices.
出处
《广东医学》
CAS
CSCD
2002年第4期370-372,共3页
Guangdong Medical Journal
