摘要
目的 :探讨提高常年性变应性鼻炎 (PAR)疗效的治疗方法。方法 :将 10 5例 PAR患者随机分为 A、 B两组 ,A组 5 8例 ,联合使用鼻腔局部应用类固醇二丙酸倍氯松、抗组胺药盐酸西替利嗪和鼻内窥镜下筛前神经射频治疗 ,B组 4 7例 ,联合使用二丙酸倍氯松、盐酸西替利嗪综合治疗。结果 :随访 1年 ,A组总有效率达 94 .83% (其中显效 4 2例 ) ,B组为 95 .74 %(其中显效 30例 ) ;A组复发率 5 1.72 % ,B组为 72 .34% ,但复发病例 90 .6 3% (5 8/ 6 4 )的复发症状较治疗前为轻。两组总有效率经χ2 检验差异无显著性 (P >0 .0 5 ) ,复发率差异有显著性 (P <0 .0 5 )。 A、 B两组均无严重并发症发生。结论 :综合疗法治疗 PAR具有设计合理 ,疗效显著 ,疗程短等优点 。
Objective:To study the effect of combined modality therapy on perennial allergic rhinitis (PAR) Method:105 cases of PAR were randomized to receive a 4 weeks treatment with either combined beclomethasone dipropionate nasal spray(BDP),cetirizine hydrochloride,ethmoidal nerve radiofrequency treatment (group A,n=58),or combined BDP,cetirzine hydrochloride (group B,n=47),and half dose combined BDP,cetirzine hydrochloride was used for improving the recurrence symptoms in one year follow up Result:The overall effective(excellent/good) rate was 94 83% for group A(excellent 72 41%)and 95 74% for group B(excellent 63 83%) respectively The recurrence rate was 51 72% for group A and 72 34% for group B respectively,but 58 recurrence cases symptoms were lighter than pre treatment There was no statistical differece (P>0 05) between the groups in efficacy,but the recurrence rate in the group A was lower significantly than that in group B (P<0 05) All treatments were well tolerated,and no serious adverse events occurred Conclusion:The reasonable combined modality therapy is aimed at the complicated pathogenesis of PAR,and the curative effect is satisfactory,so it is a good way to treat PAR
出处
《广西医学》
CAS
2002年第4期455-457,共3页
Guangxi Medical Journal
