摘要
Results of a researeh on the immunohistochemical localization of angiotensin Il(A.NG lI)in oocyte of mouse is reported.The results indicate that the distribution of ANG II was detected inthe luteal,thecal.stroma cells and blood of ovary in addition to the positive localization displayed in thecytoplasm and cell membrane of oocyte.None of staining reaction was found in the granular cells andcumulus cells.The positive immuno-reaction of ANG Il could also be detected in the course ofresumption of meiosis in oocytes.which were in the developmental phases of germinal vesiele breakingdown and extrusion of the first polar body.Therefore,A.NG II may play an important role in thecourses of the formation and developrment of ovarian follicle and maturatíon of oocyte.
本文研究了血管紧张素Ⅱ在小鼠卵母细胞中的免疫组织化学定位,结果表明血管紧张素Ⅱ不仅分布在卵巢内的黄体细胞,卵泡的膜细胞,基质和血管,在恢复减数分裂过程中,处于生发泡破裂和第一极体排放期的卵母细胞内也检测到血管紧张素Ⅱ的免疫阳性物,因此,血管紧张素Ⅱ有可能在卵泡的生长发育和卵母细胞的成熟过程中起着重要作用。
基金
supported by Grants of State Key Laboratory of Reproductive Biology,Institute of Zoology,Chinese Academy of Sciences,China
