摘要
目的:探讨无淋巴结肿大的鼻咽癌患者颈部不同剂量预防性照射的远期疗效。方法:把59例经CT颈部增强扫描结果为无淋巴结肿大的初治鼻咽癌患者分为Ⅰ组38例和Ⅱ组21例行颈部预防性照射,放射剂量Ⅰ组为46Gy～48Gy,Ⅱ组为50Gy～54Gy,连续6周～7周,随诊3年观察两组的疗效差异。结果:两组比较,3年鼻咽复发率(8%,10%)、3年颈淋巴结复发率(3%,5%)和3年生存率(95%,91%)均无统计学意义,两组各有1例出现锁骨上淋巴结复发。结论:对无淋巴结肿大的鼻咽癌初治患者行颈部预防照射,46Gy～48Gy组和50Gy～54Gy组比较,放射治疗后3年的疗效比较无统计学意义。
Objective:To study the influence of different d ose of preventive cervical irradiation on outcome of NPC without signs of cervical lymph node metasta sis.Methods :Fifty-nine NPC patients without sig ns of cervical lymph node metastasis on CT en-hancement contrast scan were random ly divided into two groups.The dose o f cervical preventive irradiation w as 46Gy ～48Gy in group 1and 50Gy ～54Gy in group 2.All patients were followed up for 3years.Results:Three-year nasopharyngeal recurre nt rate was 8%in group 1and 10%in group 2.Cervical lymph node recurrent rate was 3%and 5%respectively.Three-year su rvival rate was 95%and 91%,respectively.There was no statistical difference between the two group s.Each group had 1patient with lymph node recurrence.Conclusion:There was no significant difference in three-year curative effect betwe en cervical irradiation of 46Gy ～48Gy and 50Gy ～54Gy in NPC patients wi thout signs of cervical lymph node me tastasis.
出处
《新医学》
北大核心
2002年第3期147-148,共2页
Journal of New Medicine
关键词
鼻咽癌
CT
诊断
放射疗法
剂量效应
疗效
治疗
Tumor Radiation therapy Dose-effect relationship Recurrence Comparative study
