摘要
目的:观察经皮穿刺椎体成形术(PVP)在良、恶性椎体病变中的疗效、并发症及随访结果,探讨相关机理。方法:在CT定位下PVP治疗患者86例,采用疼痛调查表进行疗效评估,定期随访及影像学复查。结果:良性病变94.7%有效且长期效果稳定。转移瘤87.7%有效且3个月不变,4～6个月降到75.4%。发现19.8%有新骨形成或重新骨化现象。并发症少,轻微且易于处理。结论:PVP治疗椎体溶骨性或钙缺失性病变疗效好且稳定,良性优于恶性。PVP有抑制肿瘤生长及促进骨生成作用,机理复杂可能是多种因素综合作用的结果。PVP适用范围广、操作简单、疗效确实、不良反应少,可进一步推广应用。
Objective:To determine the efficacy of percutaneous vertebroplasty(PVP)in treating benign or malignant spinal lesions that result in pain and instability.Methods:Eighty-six patients(male67,female19,aged31～70years)underwent 117percutaneous injections of bone cement into vertebra under CT guidance.Results:The effective rate of benign lesions was94.7%,and the lesions were stable until today.The effective rate of malignant lesions was87.7%and were stable in the first three months,the effective rate reduced to75.4%in4to6months.Osteogenesis or ossification was observed in19.8%of le-sions that were treated by PVP.Conclusion:The curative effect of PVP which was used to treat osteolytic or calciprivic le-sions is better and stable.The curative effect of PVP in benign lesions is better than malignant.PVP have the effect to inhibit tumor growth and promote ossification.The mechanism of PVP is complex,its effects result from many factors.The advan-tages of PVP are wide application,simple-operation,reliable effect and only few complications.It can be widely applied.
出处
《中国临床医学影像杂志》
CAS
2002年第1期45-49,共5页
Journal of China Clinic Medical Imaging
基金
陕西省自然科学基金资助项目(编号:98SM41)
