摘要
目的 评价全民食盐加碘对甲状腺疾病的影响。方法 观察福州市某大医院1990—1999年在采取全民食盐加碘干预措施前后甲状腺功能亢进（甲亢）等甲状腺疾病的发病率变化。结果 食盐加碘当年甲亢和桥本氏病发病率分别为531.0和238.3/10万人,比加碘前每年157.7和6.9/10万人有明显上升,1997年甲亢发病率达到高峰,1998年两者发病率逐年下降,1999年下降至加碘前水平;加碘后人群甲亢和桥本氏病发病的相对危险度也呈类似的变化规律;1995年 8月食盐加碘前甲亢发病率306.37/10万人就已明显高于1994年的157.7/10万人。结论 近几年甲亢和桥本氏病发病率上升的原因比较复杂,甲亢发病率本身就存在上升趋势,个别病例可能与补碘有关,且目前甲亢和桥本氏病发病率都恢复至加碘前水平,因此现有碘摄入量对人群是安全的。
Objective To evaluate the effect of universal salt iodization(USI) on the incidence of thyroid disease. Methods A research for change of the incidence of hyperthyroidism and other thyroid disease was carried out in a large hospital in Fuzhou city before and after USI during 1990-1999. Results After uiversal salt iodiza-tion the incidence of hyperthyroidism was 531. 0 per 100 000 person and Hashimoto's thyroiditis was 283. 3 per 100 000 person in those years. The incidence of hyperthyroidism and Hashimoto's thyroiditis were significantly higher than that before USI (they were 157. 7 per 100 000 person and 6. 9 per 100 000 person). The incidence of hyperthyroidism reached a high peak in 1997 and than decreased year after year. The incidence of hyperthyroidism and Hashimoto's thyroiditis in 1999 were the same height as that before USI. The relative risk(RR) for hyperthyroidism and Hashimoto's thyroiditis was similar changes. In addition that the incidence of hyperthyroidism was 306. 37 per 100 000 person before USI in Aug. 1995 was significantly higher that was 157. 7 per 100 000 person in 1994. Conclusions It was complicated that the incidence of hyperthyroidism and Hashimoto's thyroiditis was going up in recent years. There was tending to rise in the incidence of hyperthyroidism itself. Some patients maybe related to the iodine intake level, but now the incidence of hyperthyroidism and Hashimoto's thyroiditis was the same height as that before USI. So for, the iodine intake level within the safe range for the population in the studies area.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2002年第2期149-151,共3页
Chinese Jouranl of Endemiology
