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氯雷酊的制备及临床应用 被引量:2

Preparation and Clinical Use of Tincture Chloramphenicol and Resorcinol
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摘要 目的:提供一种有效治疗寻常性痤疮的医院制剂及质量控制方法。方法:以75%乙醇为溶媒配制氯雷酊,以HPLC法测定含量。结果:以溶解法配制氯雷酊,工艺简单;采用HPLC法测定氯霉素和间苯二酚的含量,结果准确,重现性好。结论:该制剂制备简单,疗效肯定,适于作为医院制剂。 Objective: To provide a preperation for treating acne vnlgaris and a method for quality control. Method: 75% alcohol was used as solvent to prepare the tincture chloramphenicol and resorcinol. The concentration was determined by HPLC. Result: The technology for producing the tincture chloramphenicol and resorcinol with dissolution method was simple. The result of determining chloramphenicol and resorcinol by HPLC was accurate and a good reproducibility. Conclusion: The tincture chloramphenicol and resorcinol is easy in preparing process and the curative effect is definite. It is suitable to be used in hospital.
作者 阮丽萍 张梅
出处 《中国药师》 CAS 2002年第3期155-156,共2页 China Pharmacist
关键词 氯霉素 间苯二酚 HPLC法 氯雷酊 质量控制 寻常性痤疮 Chloramphemicol Resoremol HPLC
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