摘要
比较了猪囊虫头节抗原(CSAg)、囊壁抗原(CWAg)斑点(ELISA)和免疫酶染色试验(IEST)在脑囊虫病诊断中的敏感性、特异性和交叉反应.CSAg、CWAg Dot-ELISA 的检出阳性率分别是94.6%(53/56)和96.4%(54/56),IEST 的阳性率为98.2%.两种方法与正常人、并殖吸虫病和华支睾吸虫病患者血清均无假阳性反应、但与细粒棘球蚴病患者血清均有交叉反应.
In this paper,the results of CSAg Dot-ELISA and IEST with frozen section of cysticerus cellulosae as antigesn in the diagnosis neurocysticercosis were compared.Positive rales of CSAg,CWAg Dot-ELISA and IEST were 94.6% (53/56),96.4% (54/56) and 98.2%(55/56) respectively.No cross-reaction was observed with sera from cases oF conorchiasis and paragonimiasis,while none of the 50 serum samples from normal controls was found positive.CSAg,CWAg Dot-ELISA and IEST with serum specimens from echinococcosis were 40.9% (9/22),22.7%(5/22) and 18.1%(4/22) respectively.The results showed both Dot-ELISA and IEST with frozen sections as antigens in the diagnosis of neurocysticercosis were considered to be of higher sensitivity and specificity.
关键词
脑囊虫病
免疫诊断
囊壁抗原
antigen of scolex of cys■icerus cellulosae
an igen of cyst wall
Dot-ELISA
IEST
