摘要
目的 报告放射治疗为主综合治疗 40例 (NSCLC)的近期疗效。方法 从 1993年 2月至 1999年 8月 ,经病理组织学或细胞学确诊的 40例不能手术的Ⅲ期NSCLC分为两组 :A组辅助化疗 +白细胞介素 -2 +放射治疗 :B组单纯放射治疗。结果 治疗后 ,A组病人CR 3例 (16 7% ) ,PR 13 (72 2 % ) ,有效率为 88 9% ;B组病人CR 2例 (10 5 % ) ,PR 9例 (4 7 4% ) ,有效率为 5 7 9%。有效率比较有显著差异 (P <0 .0 5 )。放、化疗反应均可耐受。结论 综合治疗能加快肿瘤消散 ,增强机体抗瘤能力 ,提高不能手术的NSCLC的近期疗效 。
Objective The results of radiotherapy and adjuvant chemotherapy in the treatment of 40 cases of stage Ⅲ non small lung cancer(NSCLC) were reported.Method From February 1993 to August 1999,40 patients with inoperable stage Ⅲ NSCLC were randomized into two groups:Group A chemotherapy plus radiation and IL-2,Group B radiotherapy alone.Results Overall response rate was 57.9% in Group B,with 2 cases of CR and 9 cases of PR,as contrast to 88.9% in Group A,with 3 cases of CR and 13 cases of PR( P<0.05 ).Conclusion The therapeutic results are significantly better in the combination treatmrent group than those in the group receiving radiotherapy alone.In addition,IL-2 was effective in significantly reducing the occurrence of systemic side effects of radiotherapy and radiotherapy plus chemotherapy.
出处
《河南肿瘤学杂志》
2002年第1期35-36,共2页
Henan Journal of Oncology
关键词
非小细胞癌
放射疗法
综合治疗
lung neoplasms
carcinoma
non small cell
radiotherapy
combined modality therapy
