摘要
目前有人提出用新的超声检查法观察胃的排空功能,并取得成功。本文介绍46例动力障碍型非溃疡性消化不良患者,用阿米替林治疗并用超声检查法观察胃排空变化,结果发现阿米替林能使患者胃排空加速,临床症状缓解,46例中有效者为39例,有效率达85%。作用机理可能为阿米替林作用于胃肠道5-羟色胺受体,使胃排空恢复正常。
This article reported that gastric emptying in 46 cases non-ulcer dyspepsia (NUD) with motility disorders was observed with ultrasonagraphic methods after treatment with amitriptylini. The results showed that amitriptylini can quicken gastric emptying and relieve clinic symptoms.Effective rate was 85%(39/46).The therapeutic mechanism was that amitriptylini can act on 5-HT receptor in gastrointestinal tract to renew gastric emptying.
出处
《胃肠病学和肝病学杂志》
CAS
1994年第3期204-205,共2页
Chinese Journal of Gastroenterology and Hepatology
关键词
阿米替林
非溃疡性消化不良
胃肠道运动
amitriptylini non-ulcer dyspepsia motion of gastrointestinal tract