摘要
目的 :探讨脑梗死急性期外围血白细胞 (WBC)与脑梗死发生发展及预后关系。方法 :对 2 812例脑梗死患者进行回顾性统计 ,以WBC计数 10× 10 9·L-1为分组标准 ,大于者此数患者归入异常组 ,小于则属于正常组 ,分别就两组的WBC在 1～ 3、4～ 6、7～ 10d三个阶段进行WBC计数 ,同时统计病死率和意识 ,并作死亡与生存患者的WBC分析。结果 :WBC异常 (升高 )组的病死率明显高于正常组 ,WBC计数逐步升高时病死率也随着递增 ,死亡组患者的WBC计数显著高于生存组患者 ,WBC计数递增与意识状态的障碍变化严重程度存在着相关性 ,同级意识状态在不同时段的白细胞变化差异无显著性意义。结论 :脑梗死早期出现WBC计数升高的机制是脑损伤达到一定的严重程度后产生的应激反应 ,是脑梗死患者病情严重与预后差的一个重要原因 ,WBC计数与结果存在明显的相关性 ,WBC数增加可作为判断脑血管病预后简便易行的指标。
Objective: To discuss the correlation of peripheral WBC in acute cerebral infarction and the development and prognosis of the disease.Methods: Rertrospective statistics of 2812 severe cerebral infarction patients were divided into two groups according to WBC count:WBC count larger than 10×10 9/L was taken as abnormal group and normal group include WBC count smaller than 10×10 9/L. WBC count at three stage(1～3,3～6,7～10d) was calculated at the same time with death rate,consciousness.An analysis of the WBC count of the dead and the survivors was made.Results: The fatality rate of abnormal groups obviously higher normal ones. The fatality rate was increasing with the rise of WBC count,which is obviously higher in the dead than in the survivors.There was correlation between the increase of WBC count the serverity of consciosness state.Conclusion: It is the stress after brain injury to a certain serverity that leads to the increase of WBC count.It's the important reason for the serious condition and poor diagnosis of the patients. As an obvious correlation is established between WBC count and the outcome,WBC count can be a simple and easy evaluation in the prognosis of cerebral vessles.
出处
《温州医学院学报》
CAS
2002年第1期26-28,共3页
Journal of Wenzhou Medical College
关键词
急性脑梗死
白细胞计数
临床意义
cerebral infarction
white blood cell
clinical significance
