摘要
摘 要：目的 评价γ-羟基丁酸（GHBA）治疗急性脑梗死的临床疗效、安全性及其对卒中灶体积的影响。方法 对97例急性脑梗死病例随机分为GHBA组、吡拉西坦对照组及空白对照组。3组均采用血栓通注射剂作为基础治疗。GHBA和吡拉西坦分别静脉滴注入日1次，共2周。应用ESS评价临床神经功能情况，利用CT片测卒中灶体积。结果 GHBA组临床疗效明显优于空白对照组，治疗后卒中灶体积小于空白对照组。GHBA和吡拉西坦之间无显著差异。结论GHBA治疗急性脑梗死有效，而且安全。
Abstract: Objective To evaluate the efficacy and safety of GHBA(agonist of GABA) treating to acute cerebral infarction. Methods The patients was divided into three groups randomly,and treated with GHBA.pirac-etam,placebo seperately. The three groups was all treated with xueshuaitong injection as a basic treatment. GHBA and piracetam was seperately added to the test groups every day lasting for two about weeks, the neurological function was evaluated with ESS. The volume of the infarct focus was measured on CT. Results The neurological function was recovered significantly better than the control group at 14 days,and the volume of infart focus was significantly less than the control group. There is no significantly difference between the two test groups. Conclusion GHBA is effective and safe in treatment to acute cerebral infarction.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2002年第1期38-40,共3页
Journal of Apoplexy and Nervous Diseases
基金
黑龙江省科学技术委员会公关项目6197
