摘要
目的 比较头孢哌酮 /舒巴坦 (舒普深 )与亚胺培南 /西司他丁 (泰能 )对中性粒细胞缺乏患者严重感染的疗效。方法 回顾性分析 5 6例中性粒细胞缺乏合并严重感染 (男 37例 ,女 19例 ,年龄 2 8a± s2 1a) ,其中 2 8例用头孢哌酮 /舒巴坦 2 .0 g加入 5 %葡萄糖 10 0 m l静滴 ,bid;2 8例用亚胺培南 /西司他丁 0 .5 g加入 5 %葡萄糖 10 0 m l静滴 ,q8h均 7～ 10 d为一疗程。结果 头孢哌酮 /舒巴坦临床有效率 89.2 8% ,痊愈率 71.42 % ;亚胺培南 /西司他丁组临床有效率 96 .42 % ,痊愈率 75 % ,两组间相差无统计学意义 (P>0 .0 5 )。结论 头孢哌酮 /舒巴坦与亚胺培南
OBJECTIVE To compare efficacy of cefoperazone/sulbactam and imipenem/cilastatin in the treatment of serious infection associated with granulocytopenic patients. METHODS Fifty-six patients with granulocytopenia (M37, F19; age 28±21 years old) were divided into two groups. Twenty-eight patients of them were treated with cefoperazone/sulbactam (0.5g +5% glucose 100ml), iv, drip, bid for 7-10 d, Twenty-eight patients were treated with imipenem/cilastatin (0.5g+5% glucose 100ml), iv, drip, q8h for 7-10 d. RESULTS The clinical effective rate of cefoperazone/sulbactam group was 89.28%, recovery rate was 71.42%; The clinical effective rate of imipenem group was 96.42%, recovery rate was 75%. No significant difference (P>0.05) was found between cefoperazone/sulbactam group and imipenem/cilastatin one. CONCLUSIONS The therapeutic effect of cefoperazone/sulbactam in the treatment of serious infection associated with granulocytopenic patients is the same as that of imipenem/cilastatin.
出处
《中华医院感染学杂志》
CAS
CSCD
2002年第2期97-98,共2页
Chinese Journal of Nosocomiology
